What is fetal fibronectin?
fFN is a protein produced during pregnancy. It acts as a biological glue, attaching the fetal sac to the uterine lining. fFN normally is present in cervico-vaginal secretions up to 22 weeks of pregnancy and again at the end of the last trimester (1 to 3 weeks before labor). fFN usually cannot be detected between 24 and 34 weeks of pregnancy (5½ to 8½ months).
fFN is a protein produced during pregnancy. It acts as a biological glue, attaching the fetal sac to the uterine lining. fFN normally is present in cervico-vaginal secretions up to 22 weeks of pregnancy and again at the end of the last trimester (1 to 3 weeks before labor). fFN usually cannot be detected between 24 and 34 weeks of pregnancy (5½ to 8½ months).
What is the fFN test?
Health care providers give the fFN test to women between 24 and 34 weeks of pregnancy. The presence of fFN during these weeks, along with symptoms of labor, suggests that the "glue" may be disintegrating ahead of schedule and alerts health care providers to a possibility of premature labor and delivery.
Health care providers give the fFN test to women between 24 and 34 weeks of pregnancy. The presence of fFN during these weeks, along with symptoms of labor, suggests that the "glue" may be disintegrating ahead of schedule and alerts health care providers to a possibility of premature labor and delivery.
The result is either positive (fFN is present) or negative (fFN is not present).
What do fFN test results mean?
Most women with symptoms of preterm labor go on to deliver at term, even without treatment (2). The fFN test can help predict which symptomatic women have a reduced risk of premature labor and delivery. Fewer than 5 percent of women with symptoms of preterm labor who have a negative fFN test result deliver within the next 2 weeks (1). Identifying symptomatic women who have a reduced risk of premature delivery is the most valuable use of this test because these women often can avoid unnecessary medical interventions, such as bedrest, prenatal corticosteroids,hospitalization and labor-suppressing (tocolytic) medications (1,3).
Most women with symptoms of preterm labor go on to deliver at term, even without treatment (2). The fFN test can help predict which symptomatic women have a reduced risk of premature labor and delivery. Fewer than 5 percent of women with symptoms of preterm labor who have a negative fFN test result deliver within the next 2 weeks (1). Identifying symptomatic women who have a reduced risk of premature delivery is the most valuable use of this test because these women often can avoid unnecessary medical interventions, such as bedrest, prenatal corticosteroids,hospitalization and labor-suppressing (tocolytic) medications (1,3).
Positive fFN test results in women with symptoms of preterm labor are less reliable. However, positive results allow health care providers and pregnant women to take preventive measures to delay labor as long as possible and to consider labor-suppressing medications.
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Yay! Days are ticking away as your little baby grows!
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